Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors

We have previously demonstrated that loss of miR-17~92 in nephron progenitors in a mouse model results in renal hypodysplasia and chronic kidney disease. Clinically, decreased congenital nephron endowment because of renal hypodysplasia is associated with an increased risk of hypertension and chronic...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Phua, Yu Leng, Chen, Kevin Hong, Hemker, Shelby L., Marrone, April K., Bodnar, Andrew J., Liu, Xiaoning, Clugston, Andrew, Kostka, Dennis, Butterworth, Michael B., Ho, Jacqueline
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6580251/
https://ncbi.nlm.nih.gov/pubmed/30838872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00450.2018
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