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Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors
We have previously demonstrated that loss of miR-17~92 in nephron progenitors in a mouse model results in renal hypodysplasia and chronic kidney disease. Clinically, decreased congenital nephron endowment because of renal hypodysplasia is associated with an increased risk of hypertension and chronic...
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| Publié dans: | Am J Physiol Renal Physiol |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6580251/ https://ncbi.nlm.nih.gov/pubmed/30838872 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00450.2018 |
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