Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury

BACKGROUND: Damage to the renal microvasculature is a hallmark of renal ischemia-reperfusion injury (IRI)–mediated AKI. The miR-17∼92 miRNA cluster (encoding miR-17, -18a, -19a, -20a, -19b-1, and -92a-1) regulates angiogenesis in multiple settings, but no definitive role in renal endothelium during...

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Dades bibliogràfiques
Publicat a:J Am Soc Nephrol
Autors principals: Chiba, Takuto, Cerqueira, Débora M., Li, Yao, Bodnar, Andrew J., Mukherjee, Elina, Pfister, Katherine, Phua, Yu Leng, Shaikh, Kai, Sanders, Brandon T., Hemker, Shelby L., Pagano, Patrick J., Wu, Yijen L., Ho, Jacqueline, Sims-Lucas, Sunder
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2021
Matèries:
Rapid Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920169/
https://ncbi.nlm.nih.gov/pubmed/33514560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020050717
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