Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury

BACKGROUND: Damage to the renal microvasculature is a hallmark of renal ischemia-reperfusion injury (IRI)–mediated AKI. The miR-17∼92 miRNA cluster (encoding miR-17, -18a, -19a, -20a, -19b-1, and -92a-1) regulates angiogenesis in multiple settings, but no definitive role in renal endothelium during...

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Bibliografski detalji
Izdano u:J Am Soc Nephrol
Glavni autori: Chiba, Takuto, Cerqueira, Débora M., Li, Yao, Bodnar, Andrew J., Mukherjee, Elina, Pfister, Katherine, Phua, Yu Leng, Shaikh, Kai, Sanders, Brandon T., Hemker, Shelby L., Pagano, Patrick J., Wu, Yijen L., Ho, Jacqueline, Sims-Lucas, Sunder
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2021
Teme:
Rapid Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920169/
https://ncbi.nlm.nih.gov/pubmed/33514560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020050717
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