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Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling

An integral aspect of innate immunity is the ability to detect foreign molecules of viral origin to initiate antiviral signaling via pattern recognition receptors (PRRs). One such receptor is the RNA helicase retinoic acid inducible gene 1 (RIG-I), which detects and is activated by 5’triphosphate un...

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Foilsithe in:Biochem J
Main Authors: Vaughn, Lauren S., Chukwurah, Evelyn, Patel, Rekha C
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919947/
https://ncbi.nlm.nih.gov/pubmed/33459340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200987
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