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Opposite actions of two dsRNA-binding proteins PACT and TRBP on RIG-I mediated signaling

An integral aspect of innate immunity is the ability to detect foreign molecules of viral origin to initiate antiviral signaling via pattern recognition receptors (PRRs). One such receptor is the RNA helicase retinoic acid inducible gene 1 (RIG-I), which detects and is activated by 5’triphosphate un...

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Detalles Bibliográficos
Publicado en:Biochem J
Main Authors: Vaughn, Lauren S., Chukwurah, Evelyn, Patel, Rekha C
Formato: Artigo
Idioma:Inglês
Publicado: 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7919947/
https://ncbi.nlm.nih.gov/pubmed/33459340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200987
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