Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infections. While the diagnostic value of anti‐N antibodies is clear, their role in immunity is not. This is because while they are non‐neutralising, they somehow clear infection by coronavirus, influenza and LCMV in vivo. Here,...

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Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Caddy, Sarah L, Vaysburd, Marina, Papa, Guido, Wing, Mark, O’Connell, Kevin, Stoycheva, Diana, Foss, Stian, Terje Andersen, Jan, Oxenius, Annette, James, Leo C
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917548/
https://ncbi.nlm.nih.gov/pubmed/33258165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106228
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