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TRIM21—From Intracellular Immunity to Therapy

Tripartite motif containing-21 (TRIM21) is a cytosolic ubiquitin ligase and antibody receptor that provides a last line of defense against invading viruses. It does so by acting as a sensor that intercepts antibody-coated viruses that have evaded extracellular neutralization and breached the cell me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Foss, Stian, Bottermann, Maria, Jonsson, Alexandra, Sandlie, Inger, James, Leo C., Andersen, Jan Terje
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722209/
https://ncbi.nlm.nih.gov/pubmed/31555278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02049
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