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TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
Ab-coated viruses can be detected in the cytosol by the FcR tripartite motif-containing 21 (TRIM21), which rapidly recruits the proteasomal machinery and triggers induction of immune signaling. As such, TRIM21 plays a key role in intracellular protection by targeting invading viruses for destruction...
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| Izdano u: | J Immunol |
|---|---|
| Glavni autori: | , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4977002/ https://ncbi.nlm.nih.gov/pubmed/26962230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502601 |
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