Interaction with Both Domain I and III of Albumin Is Required for Optimal pH-dependent Binding to the Neonatal Fc Receptor (FcRn)

Albumin is an abundant blood protein that acts as a transporter of a plethora of small molecules like fatty acids, hormones, toxins, and drugs. In addition, it has an unusual long serum half-life in humans of nearly 3 weeks, which is attributed to its interaction with the neonatal Fc receptor (FcRn)...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Sand, Kine Marita Knudsen, Bern, Malin, Nilsen, Jeannette, Dalhus, Bjørn, Gunnarsen, Kristin Støen, Cameron, Jason, Grevys, Algirdas, Bunting, Karen, Sandlie, Inger, Andersen, Jan Terje
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Protein Structure and Folding
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263865/
https://ncbi.nlm.nih.gov/pubmed/25344603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587675
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