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Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based Therapeutics

The neonatal Fc receptor (FcRn) was first found to be responsible for transporting antibodies of the immunoglobulin G (IgG) class from the mother to the fetus or neonate as well as for protecting IgG from intracellular catabolism. However, it has now become apparent that the same receptor also binds...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Sand, Kine Marita Knudsen, Bern, Malin, Nilsen, Jeannette, Noordzij, Hanna Theodora, Sandlie, Inger, Andersen, Jan Terje
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306297/
https://ncbi.nlm.nih.gov/pubmed/25674083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00682
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