Intracellular antibody receptor TRIM21 prevents fatal viral infection

Host species have evolved mechanisms that can inhibit pathogen replication even after a cell has been successfully invaded. Here we show that tripartite-motif protein 21 (TRIM21), a ubiquitously expressed E3 ubiquitin ligase that targets viruses inside the cytosol, protects mice against fatal viral...

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Detaylı Bibliyografya
Asıl Yazarlar: Vaysburd, Marina, Watkinson, Ruth E., Cooper, Helen, Reed, Martin, O’Connell, Kevin, Smith, Jackie, Cruickshanks, James, James, Leo C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725055/
https://ncbi.nlm.nih.gov/pubmed/23840060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301918110
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