Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity

Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infections. While the diagnostic value of anti‐N antibodies is clear, their role in immunity is not. This is because while they are non‐neutralising, they somehow clear infection by coronavirus, influenza and LCMV in vivo. Here,...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Caddy, Sarah L, Vaysburd, Marina, Papa, Guido, Wing, Mark, O’Connell, Kevin, Stoycheva, Diana, Foss, Stian, Terje Andersen, Jan, Oxenius, Annette, James, Leo C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917548/
https://ncbi.nlm.nih.gov/pubmed/33258165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106228
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