Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge

Designing immunogens and improving delivery methods eliciting protective immunity is a paramount goal of HIV vaccine development. A comparative vaccine challenge study was performed in rhesus macaques using clade C HIV Envelope (Env) and SIV Gag antigens. One group was vaccinated using co-immunizati...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Malherbe, Delphine C., Vang, Lo, Mendy, Jason, Barnette, Philip T., Spencer, David A., Reed, Jason, Kareko, Bettie W., Sather, D. Noah, Pandey, Shilpi, Wibmer, Constantinos K., Robins, Harlan, Fuller, Deborah H., Park, Byung, Lakhashe, Samir K., Wilson, James M., Axthelm, Michael K., Ruprecht, Ruth M., Moore, Penny L., Sacha, Jonah B., Hessell, Ann J., Alexander, Jeff, Haigwood, Nancy L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917243/
https://ncbi.nlm.nih.gov/pubmed/33658998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.626464
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