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Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure

Mitochondrial morphology plays a critical role in regulating mitochondrial and cellular function. It is well established that oxidative stress and mitochondrial injury are central to acetaminophen (APAP) hepatotoxicity. However, the role of mitochondrial dynamics, namely the remodeling of mitochondr...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Umbaugh, David S, Nguyen, Nga T, Jaeschke, Hartmut, Ramachandran, Anup
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916734/
https://ncbi.nlm.nih.gov/pubmed/33432343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa188
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