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Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure

Mitochondrial morphology plays a critical role in regulating mitochondrial and cellular function. It is well established that oxidative stress and mitochondrial injury are central to acetaminophen (APAP) hepatotoxicity. However, the role of mitochondrial dynamics, namely the remodeling of mitochondr...

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Dettagli Bibliografici
Pubblicato in:Toxicol Sci
Autori principali: Umbaugh, David S, Nguyen, Nga T, Jaeschke, Hartmut, Ramachandran, Anup
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916734/
https://ncbi.nlm.nih.gov/pubmed/33432343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa188
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