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Mitochondrial Membrane Potential Drives Early Change in Mitochondrial Morphology After Acetaminophen Exposure

Mitochondrial morphology plays a critical role in regulating mitochondrial and cellular function. It is well established that oxidative stress and mitochondrial injury are central to acetaminophen (APAP) hepatotoxicity. However, the role of mitochondrial dynamics, namely the remodeling of mitochondr...

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Bibliografiske detaljer
Udgivet i:Toxicol Sci
Main Authors: Umbaugh, David S, Nguyen, Nga T, Jaeschke, Hartmut, Ramachandran, Anup
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916734/
https://ncbi.nlm.nih.gov/pubmed/33432343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa188
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