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A mitochondrial journey through acetaminophen hepatotoxicity
Acetaminophen (APAP) overdose is the leading cause of acute liver failure in the United States and APAP-induced hepatotoxicity is initiated by formation of a reactive metabolite which depletes hepatic glutathione and forms protein adducts. Studies over the years have established the critical role of...
Kaydedildi:
| Yayımlandı: | Food Chem Toxicol |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7254872/ https://ncbi.nlm.nih.gov/pubmed/32209353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2020.111282 |
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