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Novel strategies for the treatment of acetaminophen hepatotoxicity

INTRODUCTION: Acetaminophen (APAP) hepatotoxicity is the leading cause of acute liver failure in the western world. Despite extensive investigations into the mechanisms of cell death, only a single antidote, N-acetylcysteine, is in clinical use. However, there have recently been more efforts made to...

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Bibliographic Details
Published in:Expert Opin Drug Metab Toxicol
Main Authors: Akakpo, Jephte Y., Ramachandran, Anup, Jaeschke, Hartmut
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606761/
https://ncbi.nlm.nih.gov/pubmed/32862728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17425255.2020.1817896
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