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Mitochondrial Damage and Biogenesis in Acetaminophen-induced Liver Injury
Liver injury and acute liver failure caused by acetaminophen (APAP) overdose is the clinically most important drug toxicity in western countries. Mechanistic investigations have revealed a central role of mitochondria in the pathophysiology. Excess formation of the reactive metabolite N-acetyl-p-ben...
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| Publicado no: | Liver Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7351365/ https://ncbi.nlm.nih.gov/pubmed/32655976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.livres.2019.10.002 |
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