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Mitochondrial Damage and Biogenesis in Acetaminophen-induced Liver Injury

Liver injury and acute liver failure caused by acetaminophen (APAP) overdose is the clinically most important drug toxicity in western countries. Mechanistic investigations have revealed a central role of mitochondria in the pathophysiology. Excess formation of the reactive metabolite N-acetyl-p-ben...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Liver Res
Päätekijät: Jaeschke, Hartmut, Duan, Luqi, Nguyen, Nga, Ramachandran, Anup
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7351365/
https://ncbi.nlm.nih.gov/pubmed/32655976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.livres.2019.10.002
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