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Role of Extracellular Vesicles in Release of Protein Adducts after Acetaminophen-induced Liver Injury in Mice and Humans
Formation of acetaminophen (APAP) protein adducts are a critical feature of APAP hepatotoxicity, and circulating protein adducts have recently been utilized in bioassays for identification of APAP overdose in humans. Despite their clinical significance, mechanisms of adduct release into the circulat...
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| Pubblicato in: | Toxicol Lett |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6338225/ https://ncbi.nlm.nih.gov/pubmed/30447259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2018.11.005 |
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