4-Methylpyrazole Protects Against Acetaminophen-induced Acute Kidney Injury

Acetaminophen (APAP) hepatotoxicity is the most common cause of acute liver failure in the United States, and while a significant percentage of APAP overdose patients develop kidney injury, molecular mechanisms involved in APAP-induced nephrotoxicity are relatively unknown. We have shown that 4-meth...

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Опубликовано в: :Toxicol Appl Pharmacol
Главные авторы: Akakpo, Jephte Y., Ramachandran, Anup, Orhan, Hilmi, Curry, Steven C., Rumack, Barry H., Jaeschke, Hartmut
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7888547/
https://ncbi.nlm.nih.gov/pubmed/33157119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2020.115317
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