Promoter-proximal CTCF-binding promotes long-range-enhancer dependent gene activation

The CCCTC-binding factor (CTCF) works together with the cohesin complex to drives the formation of chromatin loops and topologically associating domains, but its role in gene regulation has not been fully defined. Here, we investigated the effects of acute CTCF loss on chromatin architecture and tra...

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Detaylı Bibliyografya
Yayımlandı:Nat Struct Mol Biol
Asıl Yazarlar: Kubo, Naoki, Ishii, Haruhiko, Xiong, Xiong, Bianco, Simona, Meitinger, Franz, Hu, Rong, Hocker, James D., Conte, Mattia, Gorkin, David, Yu, Miao, Li, Bin, Dixon, Jesse R., Hu, Ming, Nicodemi, Mario, Zhao, Huimin, Ren, Bing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7913465/
https://ncbi.nlm.nih.gov/pubmed/33398174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00539-5
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