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Double strand breaks (DSBs) as indicators of genomic instability in PATRR-mediated translocations

Genomic instability contributes to a variety of potentially damaging conditions, including DNA-based rearrangements. Breakage in the form of double strand breaks (DSBs) increases the likelihood of DNA damage, mutations and translocations. Certain human DNA regions are known to be involved in recurre...

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Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Correll-Tash, Sarah, Lilley, Brenna, Salmons IV, Harold, Mlynarski, Elisabeth, Franconi, Colleen P, McNamara, Meghan, Woodbury, Carson, Easley, Charles A, Emanuel, Beverly S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906754/
https://ncbi.nlm.nih.gov/pubmed/33258468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa251
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