Double strand breaks (DSBs) as indicators of genomic instability in PATRR-mediated translocations

Genomic instability contributes to a variety of potentially damaging conditions, including DNA-based rearrangements. Breakage in the form of double strand breaks (DSBs) increases the likelihood of DNA damage, mutations and translocations. Certain human DNA regions are known to be involved in recurre...

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Publicat a:Hum Mol Genet
Autors principals: Correll-Tash, Sarah, Lilley, Brenna, Salmons IV, Harold, Mlynarski, Elisabeth, Franconi, Colleen P, McNamara, Meghan, Woodbury, Carson, Easley, Charles A, Emanuel, Beverly S
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
General Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906754/
https://ncbi.nlm.nih.gov/pubmed/33258468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa251
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