Double strand breaks (DSBs) as indicators of genomic instability in PATRR-mediated translocations

Genomic instability contributes to a variety of potentially damaging conditions, including DNA-based rearrangements. Breakage in the form of double strand breaks (DSBs) increases the likelihood of DNA damage, mutations and translocations. Certain human DNA regions are known to be involved in recurre...

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Bibliografiska uppgifter
I publikationen:Hum Mol Genet
Huvudupphovsmän: Correll-Tash, Sarah, Lilley, Brenna, Salmons IV, Harold, Mlynarski, Elisabeth, Franconi, Colleen P, McNamara, Meghan, Woodbury, Carson, Easley, Charles A, Emanuel, Beverly S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2020
Ämnen:
General Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906754/
https://ncbi.nlm.nih.gov/pubmed/33258468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa251
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