Double strand breaks (DSBs) as indicators of genomic instability in PATRR-mediated translocations

Genomic instability contributes to a variety of potentially damaging conditions, including DNA-based rearrangements. Breakage in the form of double strand breaks (DSBs) increases the likelihood of DNA damage, mutations and translocations. Certain human DNA regions are known to be involved in recurre...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Correll-Tash, Sarah, Lilley, Brenna, Salmons IV, Harold, Mlynarski, Elisabeth, Franconi, Colleen P, McNamara, Meghan, Woodbury, Carson, Easley, Charles A, Emanuel, Beverly S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
General Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7906754/
https://ncbi.nlm.nih.gov/pubmed/33258468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa251
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