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Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler
Virtually all aspects of cell biology are regulated by a ubiquitin code where distinct ubiquitin chain architectures guide the binding events and itineraries of modified substrates. Various combinations of E2 and E3 enzymes accomplish chain formation by forging isopeptide bonds between the C-terminu...
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| 發表在: | Nat Chem Biol |
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| Main Authors: | , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904580/ https://ncbi.nlm.nih.gov/pubmed/33288957 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-00696-0 |
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