Paramagnetic NMR in drug discovery

অনুযায়ী Softley, Charlotte A., Bostock, Mark J., Popowicz, Grzegorz M., Sattler, Michael
প্রকাশিত J Biomol NMR (2020)

Structure determination of the seven-helical transmembrane receptor sensory rhodopsin II by solution NMR spectroscopy

অনুযায়ী Gautier, Antoine, Mott, Helen R., Bostock, Mark J., Kirkpatrick, John P., Nietlispach, Daniel
প্রকাশিত 2010

Insight into partial agonism by observing multiple equilibria for ligand-bound and G(s)-mimetic nanobody-bound β(1)-adrenergic receptor

অনুযায়ী Solt, Andras S., Bostock, Mark J., Shrestha, Binesh, Kumar, Prashant, Warne, Tony, Tate, Christopher G., Nietlispach, Daniel
প্রকাশিত Nat Commun (2017)

An Adaptable Phospholipid Membrane Mimetic System for Solution NMR Studies of Membrane Proteins

অনুযায়ী Chien, Chih-Ta Henry, Helfinger, Lukas R., Bostock, Mark J., Solt, Andras, Tan, Yi Lei, Nietlispach, Daniel
প্রকাশিত J Am Chem Soc (2017)

Structural Insights into the Mechanism of Negative Regulation of Single-box High Mobility Group Proteins by the Acidic Tail Domain

অনুযায়ী Stott, Katherine, Watson, Matthew, Bostock, Mark J., Mortensen, Simon A., Travers, Andrew, Grasser, Klaus D., Thomas, Jean O.
প্রকাশিত 2014

Conformational plasticity of ligand-bound and ternary GPCR complexes studied by (19)F NMR of the β(1)-adrenergic receptor

অনুযায়ী Frei, J. Niclas, Broadhurst, Richard W., Bostock, Mark J., Solt, Andras, Jones, Andrew J. Y., Gabriel, Florian, Tandale, Aditi, Shrestha, Binesh, Nietlispach, Daniel
প্রকাশিত Nat Commun (2020)

Latency, thermal stability, and identification of an inhibitory compound of mirolysin, a secretory protease of the human periodontopathogen Tannerella forsythia

অনুযায়ী Zak, Krzysztof M., Bostock, Mark J., Waligorska, Irena, Thøgersen, Ida B., Enghild, Jan J., Popowicz, Grzegorz M., Grudnik, Przemyslaw, Potempa, Jan, Ksiazek, Miroslaw
প্রকাশিত J Enzyme Inhib Med Chem (2021)

Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase

অনুযায়ী Softley, Charlotte A., Zak, Krzysztof M., Bostock, Mark J., Fino, Roberto, Zhou, Richard Xu, Kolonko, Marta, Mejdi-Nitiu, Ramona, Meyer, Hannelore, Sattler, Michael, Popowicz, Grzegorz M.
প্রকাশিত Antimicrob Agents Chemother (2020)

Correction for Softley et al., “Structure and Molecular Recognition Mechanism of IMP-13 Metallo-β-Lactamase”

অনুযায়ী Softley, Charlotte A., Zak, Krzysztof M., Bostock, Mark J., Fino, Roberto, Zhou, Richard Xu, Kolonko, Marta, Mejdi-Nitiu, Ramona, Meyer, Hannelore, Sattler, Michael, Popowicz, Grzegorz M.
প্রকাশিত Antimicrob Agents Chemother (2020)

Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

অনুযায়ী Liwocha, Joanna, Krist, David T., van der Heden van Noort, Gerbrand J., Hansen, Fynn M., Truong, Vinh H., Karayel, Ozge, Purser, Nicholas, Houston, Daniel, Burton, Nicole, Bostock, Mark J., Sattler, Michael, Mann, Matthias, Harrison, Joseph S., Kleiger, Gary, Ovaa, Huib, Schulman, Brenda A.
প্রকাশিত Nat Chem Biol (2020)