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Synthesis of Poly-Ubiquitin Chains Using a Bifunctional Ubiquitin Monomer
[Image: see text] An optimized large scale and highly reproducible route to orthogonally protected γ-thiolysine is reported. Its utility in the synthesis of bifunctional ubiquitin monomers is demonstrated. These ubiquitin synthons are employed in polymerization reactions giving access to synthetic p...
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| Veröffentlicht in: | Org Lett |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical
Society
2017
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5735377/ https://ncbi.nlm.nih.gov/pubmed/29172548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b03085 |
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