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Gated Proton Release During Radical Transfer at the Subunit Interface of Ribonucleotide Reductase
The class Ia ribonucleotide reductase of Escherichia coli requires strict regulation of long-range radical transfer between two subunits, α and β, through a series of redox-active amino acids (Y(122)•[β] ↔ W(48)?[β] ↔ Y(356)[β] ↔ Y(731)[α] ↔ Y(730)[α] ↔ C(439)[α]). Nowhere is this more precarious th...
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| Udgivet i: | J Am Chem Soc |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904477/ https://ncbi.nlm.nih.gov/pubmed/33353307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c07879 |
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