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Validated MALDI-TOF-MS method for anthrax lethal factor provides early diagnosis and evaluation of therapeutics
Anthrax lethal factor (LF) is a zinc-dependent endoprotease and a critical virulence factor for Bacillus anthracis, the causative agent of anthrax. The mass spectrometry (MS) method for total-LF quantification includes three steps; 1) LF specific antibody capture/concentration, 2) LF-specific hydrol...
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| Veröffentlicht in: | Anal Biochem |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7904043/ https://ncbi.nlm.nih.gov/pubmed/29224733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2017.12.007 |
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