High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures

Inhalation anthrax has a rapid progression and high fatality rate. Pathology and death from inhalation of Bacillus anthracis spores are attributed to the actions of secreted protein toxins. Protective antigen (PA) binds and imports the catalytic component lethal factor (LF), a zinc endoprotease, and...

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Publicat a:Anal Bioanal Chem
Autors principals: Boyer, Anne E., Gallegos-Candela, Maribel, Quinn, Conrad P., Woolfitt, Adrian R., Brumlow, Judith O., Isbell, Katherine, Hoffmaster, Alex R., Lins, Renato C., Barr, John R.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369318/
https://ncbi.nlm.nih.gov/pubmed/25673244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8509-5
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