High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures

Inhalation anthrax has a rapid progression and high fatality rate. Pathology and death from inhalation of Bacillus anthracis spores are attributed to the actions of secreted protein toxins. Protective antigen (PA) binds and imports the catalytic component lethal factor (LF), a zinc endoprotease, and...

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Pubblicato in:Anal Bioanal Chem
Autori principali: Boyer, Anne E., Gallegos-Candela, Maribel, Quinn, Conrad P., Woolfitt, Adrian R., Brumlow, Judith O., Isbell, Katherine, Hoffmaster, Alex R., Lins, Renato C., Barr, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369318/
https://ncbi.nlm.nih.gov/pubmed/25673244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8509-5
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