High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures

Inhalation anthrax has a rapid progression and high fatality rate. Pathology and death from inhalation of Bacillus anthracis spores are attributed to the actions of secreted protein toxins. Protective antigen (PA) binds and imports the catalytic component lethal factor (LF), a zinc endoprotease, and...

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Detalles Bibliográficos
Publicado en:Anal Bioanal Chem
Main Authors: Boyer, Anne E., Gallegos-Candela, Maribel, Quinn, Conrad P., Woolfitt, Adrian R., Brumlow, Judith O., Isbell, Katherine, Hoffmaster, Alex R., Lins, Renato C., Barr, John R.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369318/
https://ncbi.nlm.nih.gov/pubmed/25673244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8509-5
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