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Accurate and selective quantification of anthrax protective antigen in plasma by immunocapture and isotope dilution mass spectrometry

Anthrax protective antigen (83 kDa, PA83) is an essential component of two major binary toxins produced by Bacillus anthracis, lethal toxin (LTx) and edema toxin (ETx). During infection, LTx and ETx contribute to immune collapse, endothelial dysfunction, hemorrhage and high mortality. Following prot...

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Détails bibliographiques
Publié dans:Analyst
Auteurs principaux: Solano, Maria I., Woolfitt, Adrian R., Boyer, Anne E., Lins, Renato C., Isbell, Katie, Gallegos-Candela, Maribel, Moura, Hercules, Pierce, Carrie L., Barr, John R.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015108/
https://ncbi.nlm.nih.gov/pubmed/30810119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8an02479k
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