Accurate and selective quantification of anthrax protective antigen in plasma by immunocapture and isotope dilution mass spectrometry

Anthrax protective antigen (83 kDa, PA83) is an essential component of two major binary toxins produced by Bacillus anthracis, lethal toxin (LTx) and edema toxin (ETx). During infection, LTx and ETx contribute to immune collapse, endothelial dysfunction, hemorrhage and high mortality. Following prot...

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Bibliografiska uppgifter
I publikationen:Analyst
Huvudupphovsmän: Solano, Maria I., Woolfitt, Adrian R., Boyer, Anne E., Lins, Renato C., Isbell, Katie, Gallegos-Candela, Maribel, Moura, Hercules, Pierce, Carrie L., Barr, John R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015108/
https://ncbi.nlm.nih.gov/pubmed/30810119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8an02479k
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