Accurate and selective quantification of anthrax protective antigen in plasma by immunocapture and isotope dilution mass spectrometry

Anthrax protective antigen (83 kDa, PA83) is an essential component of two major binary toxins produced by Bacillus anthracis, lethal toxin (LTx) and edema toxin (ETx). During infection, LTx and ETx contribute to immune collapse, endothelial dysfunction, hemorrhage and high mortality. Following prot...

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Vydáno v:Analyst
Hlavní autoři: Solano, Maria I., Woolfitt, Adrian R., Boyer, Anne E., Lins, Renato C., Isbell, Katie, Gallegos-Candela, Maribel, Moura, Hercules, Pierce, Carrie L., Barr, John R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7015108/
https://ncbi.nlm.nih.gov/pubmed/30810119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8an02479k
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