High-sensitivity MALDI-TOF MS quantification of anthrax lethal toxin for diagnostics and evaluation of medical countermeasures

Inhalation anthrax has a rapid progression and high fatality rate. Pathology and death from inhalation of Bacillus anthracis spores are attributed to the actions of secreted protein toxins. Protective antigen (PA) binds and imports the catalytic component lethal factor (LF), a zinc endoprotease, and...

詳細記述

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書誌詳細
出版年:Anal Bioanal Chem
主要な著者: Boyer, Anne E., Gallegos-Candela, Maribel, Quinn, Conrad P., Woolfitt, Adrian R., Brumlow, Judith O., Isbell, Katherine, Hoffmaster, Alex R., Lins, Renato C., Barr, John R.
フォーマット: Artigo
言語:Inglês
出版事項: Springer Berlin Heidelberg 2015
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4369318/
https://ncbi.nlm.nih.gov/pubmed/25673244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-015-8509-5
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