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FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity
Proteostasis collapses during aging resulting, among other things, in the accumulation of damaged and aggregated proteins. The proteasome is the main cellular proteolytic system and plays a fundamental role in the maintenance of protein homeostasis. Our previous work has demonstrated that senescence...
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| Udgivet i: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7901890/ https://ncbi.nlm.nih.gov/pubmed/33634126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.625715 |
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