Загрузка...

FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity

Proteostasis collapses during aging resulting, among other things, in the accumulation of damaged and aggregated proteins. The proteasome is the main cellular proteolytic system and plays a fundamental role in the maintenance of protein homeostasis. Our previous work has demonstrated that senescence...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Front Cell Dev Biol
Главные авторы: Kapetanou, Marianna, Nespital, Tobias, Tain, Luke S., Pahl, Andre, Partridge, Linda, Gonos, Efstathios S.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901890/
https://ncbi.nlm.nih.gov/pubmed/33634126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.625715
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!