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FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity

Proteostasis collapses during aging resulting, among other things, in the accumulation of damaged and aggregated proteins. The proteasome is the main cellular proteolytic system and plays a fundamental role in the maintenance of protein homeostasis. Our previous work has demonstrated that senescence...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Kapetanou, Marianna, Nespital, Tobias, Tain, Luke S., Pahl, Andre, Partridge, Linda, Gonos, Efstathios S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901890/
https://ncbi.nlm.nih.gov/pubmed/33634126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.625715
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