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FoxO1 Is a Novel Regulator of 20S Proteasome Subunits Expression and Activity

Proteostasis collapses during aging resulting, among other things, in the accumulation of damaged and aggregated proteins. The proteasome is the main cellular proteolytic system and plays a fundamental role in the maintenance of protein homeostasis. Our previous work has demonstrated that senescence...

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Dades bibliogràfiques
Publicat a:Front Cell Dev Biol
Autors principals: Kapetanou, Marianna, Nespital, Tobias, Tain, Luke S., Pahl, Andre, Partridge, Linda, Gonos, Efstathios S.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901890/
https://ncbi.nlm.nih.gov/pubmed/33634126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.625715
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