Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction

Metabolic reprogramming between resistance and tolerance occurs within the immune system in response to sepsis. While metabolic tissues such as the liver are subjected to damage during sepsis, how their metabolic and energy reprogramming ensures survival is unclear. Employing comprehensive metabolom...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Mainali, Rabina, Zabalawi, Manal, Long, David, Buechler, Nancy, Quillen, Ellen, Key, Chia-Chi, Zhu, Xuewei, Parks, John S, Furdui, Cristina, Stacpoole, Peter W, Martinez, Jennifer, McCall, Charles E, Quinn, Matthew A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2021
Onderwerpen:
Immunology and Inflammation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901874/
https://ncbi.nlm.nih.gov/pubmed/33616039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64611
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