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Cysteine thiol oxidation on SIRT2 regulates inflammation in obese mice with sepsis
RATIONALE: Obesity increases morbidity and mortality in acute illnesses such as sepsis and septic shock. We showed previously that the early/hyper-inflammatory phase of sepsis is exaggerated in obese mice with sepsis; sirtuin 2 (SIRT2) modulates sepsis-inflammation in obesity. Evidence suggests that...
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| Publicado no: | Inflammation |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6380915/ https://ncbi.nlm.nih.gov/pubmed/30203196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-018-0881-9 |
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