Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction

Metabolic reprogramming between resistance and tolerance occurs within the immune system in response to sepsis. While metabolic tissues such as the liver are subjected to damage during sepsis, how their metabolic and energy reprogramming ensures survival is unclear. Employing comprehensive metabolom...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mainali, Rabina, Zabalawi, Manal, Long, David, Buechler, Nancy, Quillen, Ellen, Key, Chia-Chi, Zhu, Xuewei, Parks, John S, Furdui, Cristina, Stacpoole, Peter W, Martinez, Jennifer, McCall, Charles E, Quinn, Matthew A
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Immunology and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901874/
https://ncbi.nlm.nih.gov/pubmed/33616039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.64611
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