miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer

Different miRNA profiling protocols and technologies introduce differences in the resulting quantitative expression profiles. These include differences in the presence (and measurability) of certain miRNAs. We present and examine a method based on quantile normalization, Adjusted Quantile Normalizat...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Ben-Elazar, Shay, Aure, Miriam Ragle, Jonsdottir, Kristin, Leivonen, Suvi-Katri, Kristensen, Vessela N., Janssen, Emiel A. M., Kleivi Sahlberg, Kristine, Lingjærde, Ole Christian, Yakhini, Zohar
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2021
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901788/
https://ncbi.nlm.nih.gov/pubmed/33566819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008608
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