miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer

Different miRNA profiling protocols and technologies introduce differences in the resulting quantitative expression profiles. These include differences in the presence (and measurability) of certain miRNAs. We present and examine a method based on quantile normalization, Adjusted Quantile Normalizat...

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發表在:PLoS Comput Biol
Main Authors: Ben-Elazar, Shay, Aure, Miriam Ragle, Jonsdottir, Kristin, Leivonen, Suvi-Katri, Kristensen, Vessela N., Janssen, Emiel A. M., Kleivi Sahlberg, Kristine, Lingjærde, Ole Christian, Yakhini, Zohar
格式: Artigo
語言:Inglês
出版: Public Library of Science 2021
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901788/
https://ncbi.nlm.nih.gov/pubmed/33566819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008608
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