miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer

Different miRNA profiling protocols and technologies introduce differences in the resulting quantitative expression profiles. These include differences in the presence (and measurability) of certain miRNAs. We present and examine a method based on quantile normalization, Adjusted Quantile Normalizat...

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Detaylı Bibliyografya
Yayımlandı:PLoS Comput Biol
Asıl Yazarlar: Ben-Elazar, Shay, Aure, Miriam Ragle, Jonsdottir, Kristin, Leivonen, Suvi-Katri, Kristensen, Vessela N., Janssen, Emiel A. M., Kleivi Sahlberg, Kristine, Lingjærde, Ole Christian, Yakhini, Zohar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901788/
https://ncbi.nlm.nih.gov/pubmed/33566819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008608
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