miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer

Different miRNA profiling protocols and technologies introduce differences in the resulting quantitative expression profiles. These include differences in the presence (and measurability) of certain miRNAs. We present and examine a method based on quantile normalization, Adjusted Quantile Normalizat...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Ben-Elazar, Shay, Aure, Miriam Ragle, Jonsdottir, Kristin, Leivonen, Suvi-Katri, Kristensen, Vessela N., Janssen, Emiel A. M., Kleivi Sahlberg, Kristine, Lingjærde, Ole Christian, Yakhini, Zohar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901788/
https://ncbi.nlm.nih.gov/pubmed/33566819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008608
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