A trans-complementation system for SARS-CoV-2 recapitulates authentic viral replication without virulence

The biosafety level 3 (BSL-3) requirement to culture severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a bottleneck for research. Here, we report a trans-complementation system that produces single-round infectious SARS-CoV-2 that recapitulates authentic viral replication. We demonstra...

詳細記述

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書誌詳細
出版年:Cell
主要な著者: Zhang, Xianwen, Liu, Yang, Liu, Jianying, Bailey, Adam L., Plante, Kenneth S., Plante, Jessica A., Zou, Jing, Xia, Hongjie, Bopp, Nathen E., Aguilar, Patricia V., Ren, Ping, Menachery, Vineet D., Diamond, Michael S., Weaver, Scott C., Xie, Xuping, Shi, Pei-Yong
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier Inc. 2021
主題:
Resource
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901297/
https://ncbi.nlm.nih.gov/pubmed/33691138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.02.044
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