Neutralization of SARS-CoV-2 spike 69/70 deletion, E484K, and N501Y variants by BNT162b2 vaccine-elicited sera

We engineered three SARS-CoV-2 viruses containing key spike mutations from the newly emerged United Kingdom (UK) and South African (SA) variants: N501Y from UK and SA; 69/70-deletion+N501Y+D614G from UK; and E484K+N501Y+D614G from SA. Neutralization geometric mean titers (GMTs) of twenty BTN162b2 va...

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Publicat a:bioRxiv
Autors principals: Xie, Xuping, Liu, Yang, Liu, Jianying, Zhang, Xianwen, Zou, Jing, Fontes-Garfias, Camila R., Xia, Hongjie, Swanson, Kena A., Cutler, Mark, Cooper, David, Menachery, Vineet D., Weaver, Scott, Dormitzer, Philip R., Shi, Pei-Yong
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7852264/
https://ncbi.nlm.nih.gov/pubmed/33532771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.27.427998
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