A trans -complementation system for SARS-CoV-2

The biosafety level-3 (BSL-3) requirement to culture severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a bottleneck for research and countermeasure development. Here we report a trans -complementation system that produces single-round infectious SARS-CoV-2 that recapitulates authentic...

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Publicado en:bioRxiv
Main Authors: Zhang, Xianwen, Liu, Yang, Liu, Jianying, Bailey, Adam L., Plante, Kenneth S., Plante, Jessica A., Zou, Jing, Xia, Hongjie, Bopp, Nathen, Aguilar, Patricia, Ren, Ping, Menachery, Vineet D., Diamond, Michael S., Weaver, Scott C., Xie, Xuping, Shi, Pei-Yong
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory 2021
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836106/
https://ncbi.nlm.nih.gov/pubmed/33501436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.16.426970
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