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A trans -complementation system for SARS-CoV-2

The biosafety level-3 (BSL-3) requirement to culture severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a bottleneck for research and countermeasure development. Here we report a trans -complementation system that produces single-round infectious SARS-CoV-2 that recapitulates authentic...

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Bibliografiske detaljer
Udgivet i:bioRxiv
Main Authors: Zhang, Xianwen, Liu, Yang, Liu, Jianying, Bailey, Adam L., Plante, Kenneth S., Plante, Jessica A., Zou, Jing, Xia, Hongjie, Bopp, Nathen, Aguilar, Patricia, Ren, Ping, Menachery, Vineet D., Diamond, Michael S., Weaver, Scott C., Xie, Xuping, Shi, Pei-Yong
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7836106/
https://ncbi.nlm.nih.gov/pubmed/33501436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.01.16.426970
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