Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives

A small library of coumarin and their psoralen analogues EMAC10157a-b-d-g and EMAC10160a-b-d-g has been designed and synthesised to investigate the effect of structural modifications on their inhibition ability and selectivity profile towards carbonic anhydrase isoforms I, II, IX, and XII. None of t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Enzyme Inhib Med Chem
Main Authors: Meleddu, Rita, Deplano, Serenella, Maccioni, Elias, Ortuso, Francesco, Cottiglia, Filippo, Secci, Daniela, Onali, Alessia, Sanna, Erica, Angeli, Andrea, Angius, Rossella, Alcaro, Stefano, Supuran, Claudiu T., Distinto, Simona
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2021
Teme:
Brief Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899656/
https://ncbi.nlm.nih.gov/pubmed/33602041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1887171
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